March Madness betting took a break after an exciting weekend, but it all starts up tomorrow night. This is how you should make your sportsbook picks, beginning

Purdue vs Connecticut (West) – 7:07 PM ET

The top-seeded Huskies are 6.5-point favorites, and while the No.4 Boilermakers have one of the toughest defenses in the country, UConn was probably the best team in the Tournament’s first weekend. If Hasheem Thabeet stays out of foul trouble, the Huskies win running away. If he doesn’t, they’ll still cover the March Madness betting spread.

Xavier vs Pittsburgh (East) – 7:27 PM ET

The top-seeded Panthers have a 7-point spread over the No.4 Muskateers, who will be able to match Pitt’s physical play. Pitt’s stars will be the difference, especially Sam Young, who is one of the toughest players in the country to guard. Bet on Pitt, but they won’t cover the March Madness betting spread.

Missouri vs Memphis (West)  – 9:37 PM ET

No.2 Memphis is a 4.5-point favorite over No.3 Missouri in this battle of the Tigers, and while Mizzou has one of the top offenses in the country, they’re running into a Memphis team that regained their swagger in a romp over Maryland, and they may be the best defensive team in the nation. Memphis will harass their way to a win while covering the March Madness betting spread.

Villanova vs Duke (East) – 9:57 PM ET

The No.2 Blue Devils are a 2-point favorite against the No.3 Wildcats, who romped all over UCLA in the second round. Duke were a bit fortunate to beat Texas, but Villanova will have too much in the post for the smaller Blue Devils to handle. Go with ‘Nova in a March Madness betting upset.

Well, what a first March Madness betting weekend….my pick to win is still in it (Memphis), while my pick to bow out early (Duke) ruined a perfect online betting day on Saturday. Here is a look at the top team over the first weekend of the NCAA Tournament, as well as the biggest disappointment.

UConn had no problems with Chattanooga in a 103-47 romp, outrebounding the No.16 seed 57-33 as three of their players scored 20 points or more. Then the Huskies shot 57.9% and outrebounded Texas A&M 36-22 in a 92-66 thumping on Saturday. UConn covered the March Madness betting spreads easily, dominating their opponents on both ends of the floor, but the road will get tougher in the Sweet 16, where they’ll meet a tough Purdue team, and March Madness odds are giving the Huskies a 6.5-point spread in this contest.

Pittsburgh has been known as one of the great underachievers among March Madness betting players, and they proved why in wins over East Tennessee State and Oklahoma State. The Panthers had a 20.5-point line against ETSU, and had to overcome 18 turnovers to win by 10, then they just missed the 8.5-point spread against the Cowboys, winning by eight points. Next up is Xavier, and the Huskies are favored by seven points according to sportsbook odds, but they’ll have their hands full with the Muskateers, who are just as physical as the Panthers and have a great Tournament pedigree, so don’t be surprised by a March Madness betting upset.