As far as predictions go, those made surrounding the 2010 NCAA Tournament have generally been less than successful than picking a Kentucky derby odds or a World Cup Betting winner.

Still, as we look ahead to Saturday’s Final Four, sportsbook odds makers are showing confidence in

both Butler and Duke. Butler, who hasn’t lost in 2010, will look to take on the Michigan State Spartans, another underdog team that’s made it far

further than most brackets – or the current injury report would have predicted. Butler have been literally unstoppable in 2010, having not lost since

before the midway break in the season. Their hot streak has extended into tournament play – they shocked the world by knocking off Final Four odds favorite Kansas in the Elite Eight. While the

game will be far from a blowout, famed Michigan State coach Tom Izzo will have to pull some serious tricks out of his bag to damage Butler’s seemingly

impenetrable defense: The Bulldogs have allowed opponents less than 60 points in each of their tournament games thus far.

On the other side, Duke will take on the West Virginia Mountaineers, the team responsible for bouncing the second overall tournament favorite Kentucky

from action. Duke are the team most likely to be here, and they will look to cement that status by shutting down the plucky West Virginia. The

Mountaineers have stellar defense and impressive size, but Duke’s formidable defense and stellar perimeter game will prove too much for the

Mountaineers.